multiple myeloma lumps under skin

Championisme authors

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15-10-2024

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Multiple Myeloma and Lumps Under the Skin: Understanding the Connection

Multiple myeloma is a type of cancer that affects plasma cells, a type of white blood cell responsible for producing antibodies. In myeloma, these cells become cancerous and multiply uncontrollably, accumulating in the bone marrow. While bone pain is a common symptom, some individuals may experience lumps under the skin as well.

What Causes Lumps Under the Skin in Multiple Myeloma?

Lumps under the skin in multiple myeloma are often a sign of extra-medullary plasmacytoma, a rare form of myeloma that occurs outside the bone marrow. This means the cancerous plasma cells are forming tumors in other tissues, such as the skin, lungs, or lymph nodes.

According to a study published in the journal Leukemia & Lymphoma by Ikeda et al. (2006), extra-medullary plasmacytomas occur in approximately 3-5% of multiple myeloma patients. The study also found that these tumors are more commonly found in the skin, lymph nodes, and soft tissues.

Understanding Extra-Medullary Plasmacytoma

• What are they? Extra-medullary plasmacytomas are tumors made up of cancerous plasma cells. They can appear anywhere in the body, though they are most commonly found in the skin.
• How do they form? The exact cause is unclear, but it's believed that cancerous plasma cells from the bone marrow can migrate to other tissues and start forming tumors.
• What do they look like? Extra-medullary plasmacytomas can manifest as firm, painless nodules or masses under the skin. They can range in size and may be localized or widespread.

Diagnosis and Treatment of Lumps Under the Skin in Multiple Myeloma

If you discover a lump under your skin, especially if you have been diagnosed with multiple myeloma, it's essential to see a doctor immediately. The doctor will likely perform a biopsy to determine the nature of the lump. This involves taking a small sample of tissue from the lump and examining it under a microscope.

Treatment for extra-medullary plasmacytoma will depend on the specific case and may include:

• Radiation therapy: This is often used to shrink or destroy the tumor.
• Chemotherapy: Drugs are used to target and kill cancerous cells.
• Surgery: In some cases, surgery may be necessary to remove the tumor.

Living with Multiple Myeloma and Skin Lumps

While the presence of lumps under the skin can be alarming, it's important to remember that myeloma is a treatable disease. With early detection and appropriate treatment, many patients can live long and fulfilling lives.

Key Takeaways

• Lumps under the skin in multiple myeloma are often a sign of extra-medullary plasmacytoma.
• Extra-medullary plasmacytomas are rare but can occur in 3-5% of multiple myeloma patients.
• These tumors are usually painless and may be localized or widespread.
• Early diagnosis and treatment are crucial for managing extra-medullary plasmacytoma.
• While living with multiple myeloma can be challenging, with appropriate treatment and support, many patients can enjoy a good quality of life.

Important Note: This article is for informational purposes only and should not be considered medical advice. Consult your doctor if you have any concerns about your health or treatment options.

References:

• Ikeda, H., Tanaka, H., & Azuma, M. (2006). Extra-medullary plasmacytoma: Clinicopathological features and prognostic factors in 45 patients. Leukemia & Lymphoma, 47(9), 1899-1906.

Additional Information:

• The International Myeloma Foundation (IMF): https://www.myeloma.org/
• The American Cancer Society: https://www.cancer.org/