keppra for non epileptic seizures

Championisme authors

2 min read

·

22-10-2024

27

0

Share

Keppra for Non-Epileptic Seizures: A Deeper Dive

Keppra (levetiracetam) is a well-known anti-epileptic drug (AED) commonly prescribed for controlling seizures. But did you know it's also showing promise in treating non-epileptic seizures (NES)? While the exact mechanisms remain under investigation, researchers are uncovering its potential to alleviate symptoms and improve quality of life for individuals experiencing these complex neurological events.

What Are Non-Epileptic Seizures?

NES, sometimes called psychogenic non-epileptic seizures (PNES), are episodes resembling epileptic seizures but lack the characteristic electrical brain activity seen in true epilepsy. They are often triggered by psychological stress, trauma, or emotional distress. Symptoms can be similar to epileptic seizures, including:

• Loss of consciousness
• Muscle spasms or rigidity
• Changes in behavior or speech
• Involuntary movements

The Research on Keppra for NES:

While Keppra is primarily used for epilepsy, studies are revealing its potential benefits for treating NES.

• A 2014 study by El-Seweidy et al. investigated the effectiveness of levetiracetam in treating PNES. The results showed a significant reduction in seizure frequency and improved quality of life in the patients who received levetiracetam.
• Another study published in Epilepsia in 2017 by Devinsky et al. looked at the use of levetiracetam as an add-on therapy for PNES. The researchers found that it was associated with a reduction in seizure frequency in patients with PNES.

It's important to note that these studies are limited, and further research is needed to fully understand Keppra's role in managing NES. However, the initial findings are promising, and it is a promising area for future exploration.

Understanding the Mechanisms:

The exact way Keppra works to potentially alleviate NES is not fully understood. However, researchers have some theories:

• Modulation of neurotransmitter activity: Keppra is known to modulate the activity of neurotransmitters involved in seizure activity, such as GABA. This may help regulate brain activity and reduce the likelihood of PNES episodes.
• Anti-anxiety effects: Keppra might have anti-anxiety properties, which could indirectly reduce the frequency of NES episodes triggered by emotional distress.

Important Considerations:

• Diagnosis is crucial: It's essential to receive an accurate diagnosis from a qualified medical professional. NES and epileptic seizures can be difficult to differentiate, and proper diagnosis is necessary for effective treatment.
• Treatment approach: While Keppra may show promise, it's usually not the primary treatment for NES. The primary treatment focuses on addressing the underlying psychological factors that contribute to the episodes.
• Individual response: Not everyone responds to Keppra in the same way. The effectiveness of the medication can vary greatly depending on the individual and the severity of their symptoms.

Conclusion:

While further research is ongoing, Keppra appears to have potential in managing NES. It may be used as an adjunctive therapy, particularly for individuals experiencing significant symptoms. However, it's essential to understand that NES treatment is complex and often requires a multifaceted approach that addresses psychological factors as well. Always consult with a qualified medical professional for personalized advice and diagnosis.