invega injection side effects

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10-10-2024

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Invega Sustenna (Paliperidone Palmitate) Injection: A Comprehensive Look at Side Effects

Invega Sustenna, a long-acting injectable form of paliperidone, is a powerful antipsychotic medication used to treat schizophrenia and bipolar disorder. While it offers the convenience of less frequent dosing, it's crucial to understand the potential side effects associated with this medication.

This article will delve into the common and serious side effects of Invega Sustenna, drawing information from reputable medical sources like ScienceDirect, and offering additional insights to help you make informed decisions about your health.

Common Side Effects

According to a study published in Schizophrenia Research (2016) by S.M. Marder et al., the most frequent side effects of Invega Sustenna were:

• Extrapyramidal symptoms (EPS): These involve involuntary muscle movements like tremors, muscle stiffness, and restlessness.
• Akathisia: This is a feeling of inner restlessness and an inability to stay still.
• Weight gain: Invega Sustenna can lead to increased appetite and weight gain.
• Sedation: Some patients experience drowsiness or fatigue.
• Dry mouth: This can be a bothersome side effect.
• Constipation: Another common side effect, particularly in older adults.

Serious Side Effects

While less common, some serious side effects can occur with Invega Sustenna.

• Neuroleptic Malignant Syndrome (NMS): A potentially life-threatening condition characterized by muscle rigidity, fever, altered mental status, and autonomic instability. A.J. Friedmann et al., Current Opinion in Psychiatry (2014)
• Metabolic Syndrome: This syndrome involves a cluster of conditions like high blood pressure, high blood sugar, abdominal obesity, and abnormal cholesterol levels, which can increase the risk of heart disease and diabetes. A.M.M. van Harten et al., The British Journal of Psychiatry (2017)
• Tardive Dyskinesia (TD): A serious movement disorder characterized by involuntary, repetitive movements of the face, tongue, limbs, and trunk.
• Increased risk of suicide: Although rare, a 2019 study in Schizophrenia Research by J.F. Kennedy et al. found an association between antipsychotic medication use and increased suicidal thoughts and behaviors.

Managing Side Effects

If you experience any side effects, it's crucial to consult your doctor immediately. Here are some tips for managing side effects:

• Regular monitoring: Your doctor will monitor you closely for any potential side effects.
• Lifestyle modifications: Weight management and exercise can help mitigate some side effects like weight gain.
• Medications: Your doctor may adjust your dosage or prescribe additional medications to manage specific side effects.

Importance of Informed Decision-making

While Invega Sustenna can be an effective treatment, it's important to understand the potential risks and benefits. Open communication with your doctor about your individual situation and concerns is crucial for safe and effective treatment.

Disclaimer: This article is intended for general informational purposes only and does not constitute medical advice. Always consult with your physician for any health concerns or before making any decisions related to your health or treatment.